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Prognostic value of metabolic dysfunction-associated steatotic liver disease over coronary computed tomography angiography findings: comparison with no-alcoholic fatty liver disease.
Prognostic value of metabolic dysfunction-associated steatotic liver disease over coronary computed tomography angiography findings: comparison with no-alcoholic fatty liver disease.
Fuente:Cardiovascular Diabetology
Extracto:
Patients with MASLD are
likely to have a higher risk of cardiovascular disease than those with NAFLD.
Concurrent assessment of MASLD during CCTA improves the identification of
patients at a higher risk of cardiovascular disease among those with clinically
indicated CCTA.
Contributions of elevated CRP, hyperglycaemia, and type 2 diabetes to cardiovascular risk in the general population: observational and Mendelian randomization studies.
Contributions of elevated CRP, hyperglycaemia, and type 2 diabetes to cardiovascular risk in the general population: observational and Mendelian randomization studies.
Fuente:Cardiovascular Diabetology
Extracto:
Elevated concentrations of
plasma CRP and glucose are predictors of IHD and CVD death in the general
population. We found no genetic association between CRP and glucose, or vice
versa, suggesting that lowering glucose pharmacologically does not have a direct
effect on low-grade inflammation.
Cita:Cardiovasc Diabetol 2024 May 10; 23 (1) : 165.
Autor/es:Rolver, Monica G (a) Emanuelsson, Frida (b)
institución:(a) Department of Clinical Biochemistry, Copenhagen University Hospital - Herlev Gentofte, Borgmester Ib Juuls Vej 1, Herlev, 2730, Denmark. (b) Institute of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Copenhagen, 2200, Denmark.
Conflicto:Monica Gylling Rolver is part-time employed by Novo Nordisk Denmark as a student assistant. Other authors report no conflict of interest related to the present study.
Association of neutrophil-lymphocyte ratio with all-cause and cardiovascular mortality in US adults with diabetes and prediabetes
Association of neutrophil-lymphocyte ratio with all-cause and cardiovascular mortality in US adults with diabetes and prediabetes
Fuente:Bmc Endocrine Disorders
Tipo de trabajo:Estudio de cohortes
Extracto:
The findings of this
prospective cohort study conducted in the US indicate a positive association of
elevated NLR levels with heightened risks of overall and cardiovascular mortality
among adults with diabetes and prediabetes. However, potential confounding
factors for NLR and the challenge of monitoring NLR's fluctuations over time
should be further focused.
institución:(a) Department of Endocrinology and Metabolism, Guangzhou Red Cross Hospital, Jinan University, Guangzhou, 510220, Guangdong, China. (b) State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Enhanced external counterpulsation treatment improves multi-organ hemodynamics for postoperative liver transplantation patient. A case report.
Enhanced external counterpulsation treatment improves multi-organ hemodynamics for postoperative liver transplantation patient. A case report.
Fuente:Journal of Cardiothoracic Surgery
Extracto:
We report a case of
multi-organ ischemic symptoms in a post LT patient. EECP treatment can
significantly improve the quality of life via the systematic promotion of
hemodynamics.
Cita:J Cardiothorac Surg 2024 May 10; 19 (1) : 284.
Autor/es:Zeng, Xinchen (a) Jin, Xin (b)
institución:(a) Department of Liver Surgery, The Third People's Hospital of Shenzhen, Shenzhen, 518112, China. (b) Department of Liver Surgery, The Third People's Hospital of Shenzhen, Shenzhen, 518112, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Low ankle-brachial index is associated with higher cardiovascular mortality in individuals with nonalcoholic fatty liver disease.
Low ankle-brachial index is associated with higher cardiovascular mortality in individuals with nonalcoholic fatty liver disease.
Fuente:European Journal of Medical Research
Tipo de trabajo:Estudio de cohortes
Extracto:
Low ABI is independently
associated with higher cardiovascular mortality in NAFLD cases. This correlation
remains significant even in the absence of pre-existing cardiovascular disease or
diabetes.
institución:(a) Department of Geriatric Endocrinology and Metabolism, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning, 530021, Guangxi, China. (b) Department of Geriatric Endocrinology and Metabolism, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning, 530021, Guangxi, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
The Impact of Normobaric Hypoxia and Intermittent Hypoxic Training on Cardiac Biomarkers in Endurance Athletes: A Pilot Study.
The Impact of Normobaric Hypoxia and Intermittent Hypoxic Training on Cardiac Biomarkers in Endurance Athletes: A Pilot Study.
Fuente:International Journal of Molecular Sciences
Extracto:
These findings suggest that IHT at moderate
altitudes does not adversely affect cardiac muscle condition and may support
cardiac muscle adaptation, affirming the safety and efficacy of IHT as a training
method for athletes.
Claves:cardiac biomarkers, endurance athletes, hypoxia, intermittent hypoxic training
Cita:Int J Mol Sci 2024 Apr 23; 25 (9)
Autor/es:Goliniewski, Jakub (a) Czuba, Miłosz (b)
institución:(a) Department of Sports Theory, The Jerzy Kukuczka Academy of Physical Education, 40-065 Katowice, Poland. (b) Faculty of Rehabilitation, Józef Piłsudski University of Physical Education in Warsaw, 00-968 Warsaw, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Spinning Disk Confocal Microscopy for Optimized and Quantified Live Imaging of 3D Mitochondrial Network.
Spinning Disk Confocal Microscopy for Optimized and Quantified Live Imaging of 3D Mitochondrial Network.
Fuente:International Journal of Molecular Sciences
Extracto:
Conclusively, our data show that TMRM
staining outperformed JC-1 and CMXRos dyes in a (repetitive) 3D analysis of the
entire mitochondrial quantity, morphology, and membrane potential in living
cells.
Claves:CLSM, JC-1, MitoTracker Red CMX Rox, TMRM, mitochondria, spinning disk confocal microscope
Cita:Int J Mol Sci 2024 Apr 28; 25 (9)
Autor/es:Ahmadian, Somaieh (a) Lindsey, Patrick J (b)
institución:(a) Department of Toxicogenomics, Maastricht University Medical Centre+, 6229 ER Maastricht, The Netherlands. (b) GROW Research Institute for Oncology and Reproduction, Maastricht University, 6229 ER Maastricht, The Netherlands.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Lipid and Vascular Risk Unit, Department of Endocrinology and Nutrition, Hospital del Mar, 08003 Barcelona, Spain. (b) School of Medicine, Universitat Pompeu Fabra, 08003 Barcelona, Spain.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Antiplatelet Effects of Flavonoid Aglycones Are Mediated by Activation of Cyclic Nucleotide-Dependent Protein Kinases.
Antiplatelet Effects of Flavonoid Aglycones Are Mediated by Activation of Cyclic Nucleotide-Dependent Protein Kinases.
Fuente:International Journal of Molecular Sciences
Extracto:
These findings underscore the therapeutic
potential of flavonoid aglycones for clinical application as antiplatelet agents.
Claves:PDE inhibitors, antiplatelet therapy, cyclic adenosine monophosphate (cAMP), cyclic guanosine monophosphate (cGMP), flavonoids, phosphodiesterase (PDE), platelets, protein kinase A (PKA), protein kinase G (PKG), thromboxane synthase (TxS)
Cita:Int J Mol Sci 2024 Apr 29; 25 (9)
Autor/es:Balykina, Anna (a) Naida, Lidia (b)
institución:(a) Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences, Saint Petersburg 194223, Russia. (b) Faculty of General Medicine, Saint Petersburg State University, Saint Petersburg 199034, Russia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A Cross-Sectional Study of Glomerular Hyperfiltration in Polycystic Ovary Syndrome.
A Cross-Sectional Study of Glomerular Hyperfiltration in Polycystic Ovary Syndrome.
Fuente:International Journal of Molecular Sciences
Extracto:
There were
progressive eGFR decrements for PCOS-nonGH, PCOS-GH, and PCOS-SGH in the
follow-up period which, in the presence of additional factors affecting renal
function, may be clinically important in the development of CKD in PCOS.
Autor/es:Butler, Alexandra E (a) Lubbad, Walaa (b)
institución:(a) Research Department, Royal College of Surgeons in Ireland Bahrain, Busaiteen, Adliya P.O. Box 15503, Bahrain. (b) Research Department, Royal College of Surgeons in Ireland Bahrain, Busaiteen, Adliya P.O. Box 15503, Bahrain.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Autor/es:Wilnes, Bruno (a) Castello-Branco, Beatriz (b)
institución:(a) Interdisciplinary Laboratory of Medical Investigation, Unit of Pediatric Nephrology, Department of Pediatrics, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte 30130-100, MG, Brazil. (b) Interdisciplinary Laboratory of Medical Investigation, Unit of Pediatric Nephrology, Department of Pediatrics, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte 30130-100, MG, Brazil.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
JMJD6 Autoantibodies as a Potential Biomarker for Inflammation-Related Diseases.
JMJD6 Autoantibodies as a Potential Biomarker for Inflammation-Related Diseases.
Fuente:International Journal of Molecular Sciences
Extracto:
Hence, JMJD6 autoantibodies may
reflect inflammation, thereby serving as a potential biomarker for diagnosing
specific inflammation-related diseases, including stroke, AMI, DM, and cancers,
and for prediction of the prognosis in patients with EC.
institución:(a) Department of Neurological Surgery, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan. (b) Department of Biochemistry and Genetics, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Conflicto:This present study was performed in collaboration with Fujikura Kasei Co., Ltd., and Hideyuki Kuroda is an employee of Fujikura Kasei Co., Ltd. The other authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Mechanisms of Pulmonary Vasculopathy in Acute and Long-Term COVID-19
Mechanisms of Pulmonary Vasculopathy in Acute and Long-Term COVID-19
Fuente:International Journal of Molecular Sciences
Tipo de trabajo:Revisión
Extracto:
As many patients develop post-COVID symptoms, including
dyspnea, we also discuss the hypothesis of pulmonary vascular damage and
pulmonary hypertension as a sequela of the infection, which may be involved in
the pathophysiology of long COVID.
institución:(a) Translational Medicine Federation of Strasbourg (FMTS), University of Strasbourg, CRBS, Team 3072 "Mitochondria, Oxidative Stress and Muscle Protection", 1 rue Eugène Boeckel, CS 60026, 67084 Strasbourg, France. (b) Physiology and Functional Exploration Service, University Hospital of Strasbourg, 1 Place de l'hôpital, 67091 Strasbourg, France.
Conflicto:The authors declare that they have no additional financial or non-financial conflicts of interest to declare.
The Mediterranean Diet, Its Microbiome Connections, and Cardiovascular Health
The Mediterranean Diet, Its Microbiome Connections, and Cardiovascular Health
Fuente:International Journal of Molecular Sciences
Tipo de trabajo:Revisión
Extracto:
This review will
focus on the effects of MD on cardiovascular health through its action on gut
microbiota.
Claves:Mediterranean-type diet, Western-type diet, atherosclerosis, bile acids, cardiovascular disease, gut microbiota, nutrients, short-chain fatty acid, trimethylamine N-oxide
Cita:Int J Mol Sci 2024 Apr 30; 25 (9)
Autor/es:Abrignani, Vincenzo (a) Salvo, Andrea (b)
institución:(a) Internal Medicine and Stroke Care Ward, University of Palermo, 90127 Palermo, Italy. (b) Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Serum Levels of Adiponectin Are Strongly Associated with Lipoprotein Subclasses in Healthy Volunteers but Not in Patients with Metabolic Syndrome.
Serum Levels of Adiponectin Are Strongly Associated with Lipoprotein Subclasses in Healthy Volunteers but Not in Patients with Metabolic Syndrome.
Fuente:International Journal of Molecular Sciences
Extracto:
We
conclude that the presence of MS weakens or abolishes the strong associations
between adiponectin and the lipoprotein parameters observed in HVs and disturbs
the complex interplay between adiponectin and lipoprotein metabolism.
Claves:adiponectin, lipoprotein subclasses, metabolic syndrome, nuclear magnetic resonance spectroscopy
Cita:Int J Mol Sci 2024 May 6; 25 (9)
Autor/es:Klobučar, Iva (a) Habisch, Hansjörg (b)
institución:(a) Department of Cardiology, Sisters of Charity University Hospital Centre, 10000 Zagreb, Croatia. (b) Otto Loewi Research Center, Medicinal Chemistry, Medical University of Graz, 8010 Graz, Austria.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Pre-Pregnancy Obesity and Infants' Motor Development within the First Twelve Months of Life: Who Is Expected to Be the Ultimate Carrier of the Obesity Burden?
Pre-Pregnancy Obesity and Infants' Motor Development within the First Twelve Months of Life: Who Is Expected to Be the Ultimate Carrier of the Obesity Burden?
Fuente:Nutrients
Extracto:
Pre-pregnancy obesity is a critical
determinant of pregnancy outcomes and offspring early motor development, with
possible far-reaching implications for children's long-term well-being.
Addressing this issue requires a comprehensive approach that includes
preconception weight management, targeted interventions during the pregnancy and
postpartum periods, and ongoing research to better understand the underlying
mechanisms and develop effective strategies for prevention and management.
Claves:complications, early motor development, offspring, pre-pregnancy obesity
Cita:Nutrients 2024 Apr 24; 16 (9)
Autor/es:Lackovic, Milan (a) Nikolic, Dejan (b)
institución:(a) Department of Obstetrics and Gynecology, University Hospital "Dragisa Misovic", Heroja Milana Tepica 1, 11000 Belgrade, Serbia. (b) Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Validation of Nutritional Approaches to Modulate Cardiovascular and Diabetic Risk Factors in Patients with Hypertriglyceridemia or Prediabetes-The MoKaRi II Randomized Controlled Study.
Validation of Nutritional Approaches to Modulate Cardiovascular and Diabetic Risk Factors in Patients with Hypertriglyceridemia or Prediabetes-The MoKaRi II Randomized Controlled Study.
Fuente:Nutrients
Extracto:
In patients with elevated TG or fasting glucose,
implementing individualized menu plans in combination with regular counseling
sessions over 10 weeks led to a significant improvement in cardiovascular and
diabetic risk factors.
Claves:cardiovascular risk, diabetes mellitus type 2, fish oil supplementation, hypertriglyceridemia, menu plans, prediabetes
Cita:Nutrients 2024 Apr 24; 16 (9)
Autor/es:Braun, Theresa S (a) Drobner, Timo (b)
institución:(a) Junior Research Group Nutritional Concepts, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Dornburger Straße 25-29, 07743 Jena, Germany. (b) Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Dornburger Straße 25-29, 07743 Jena, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Cardiovascular Disease Burden Attributable to High Sodium Intake in China: A Longitudinal Study from 1990 to 2019.
Cardiovascular Disease Burden Attributable to High Sodium Intake in China: A Longitudinal Study from 1990 to 2019.
Fuente:Nutrients
Extracto:
The
HSI-induced CVD burden is gender-, age-, and socioeconomic-dependent. Integrated
and targeted strategies for CVD prevention are anticipated in the future
throughout China.
Claves:China, burden of disease, cardiovascular disease, high sodium intake
Cita:Nutrients 2024 Apr 26; 16 (9)
Autor/es:Jiang, Liying (a) Shen, Wanying (b)
institución:(a) Jiading Central Hospital, Shanghai University of Medicine & Health Sciences, Shanghai 201899, China. (b) Department of Prevention Medicine, College of Public Health, Shanghai University of Medicine & Health Sciences, Shanghai 201318, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The Role of Diet in the Cardiovascular Health of Childhood Cancer Survivors-A Systematic Review.
The Role of Diet in the Cardiovascular Health of Childhood Cancer Survivors-A Systematic Review.
Fuente:Nutrients
Tipo de trabajo:Revisión sistemática
Extracto:
The review results indicate the potentially
protective effects of healthy diets. However, the available research remains
preliminary and limited, underscoring the need for more rigorous, adequately
powered studies.
institución:(a) Children's Health & Exercise Research Centre (CHERC), Faculty of Health and Life Sciences, University of Exeter, Exeter EX1 2LU, UK. (b) Children's Health & Exercise Research Centre (CHERC), Faculty of Health and Life Sciences, University of Exeter, Exeter EX1 2LU, UK.
Conflicto:The authors report no conflict of interest.
Extracto:
This
consensus statement establishes a standardized approach to nutritional support,
aiming to optimize outcomes in pediatric cancer patients.
Claves:childhood cancer, nutrition, nutritional support
institución:(a) Department of Pediatrics, Pediatric Gastroenterology, Allergology and Nutrition, Medical University of Gdansk, 80-210 Gdansk, Poland. (b) Department of Pediatrics, Pediatric Gastroenterology, Allergology and Nutrition, Medical University of Gdansk, 80-210 Gdansk, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación