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Lectura recomendada:
Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis
JAMA Cardiology, 3(9):823-828
¿Cuál es el mecanismo de acción de alirocumab?
Introducción:
Los pacientes con antecedente de síndromes coronarios agudos tienen riesgo sustancial de recurrencia de eventos isquémicos, esencialmente como consecuencia de los niveles persistentemente altos de colesterol asociado a lipoproteínas de baja densidad.
Lectura recomendada:
Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome
New England Journal of Medicine, 379:2097-2107
Lectura recomendada:
Ten-year association of coronary artery calcium with atherosclerotic cardiovascular disease (ASCVD) events: the multi-ethnic study of atherosclerosis (MESA)
European Heart Journal, 39(25):2401-2408
Lectura recomendada:
Direct Oral Anticoagulants in Nonvalvular Atrial Fibrillation: Practical Considerations on the Choice of Agent and Dosing
Cardiology, 140(2):126-132
Lectura recomendada:
Effect of Escitalopram vs Placebo Treatment for Depression on Long-Term Cardiac Outcomes in Patients with Acute Coronary Syndrome: A Randomized Clinical Trial
JAMA, 320(4):350-357
Lectura recomendada:
Open-Label Study Assessing the Long-term Efficacy and Safety of Triple Olmesartan/Amlodipine/Hydrochlorothiazide Combination Therapy for Hypertension
Advances in Therapy, 31(5):561-574
Lectura recomendada:
Non–Vitamin K Antagonist Oral Anticoagulants in Patients With Atrial Fibrillation and Valvular Heart Disease
Journal of the American College of Cardiology, 69(11):1363-1371
Lectura recomendada:
History of Periodontitis Diagnosis and Edentulism as Predictors of Cardiovascular Disease, Stroke, and Mortality in Postmenopausal Women
Journal of the American Heart Association, 6(4):1-11
Lectura recomendada:
Elevated blood pressure and risk of mitral regurgitation: A longitudinal cohort study of 5.5 million United Kingdom adults
PLoS Medicine, 14(10):1-15
Lectura recomendada:
Antibiotic Prophylaxis and Incidence of Endocarditis Before and After the 2007 AHA Recommendations
Journal of the American College of Cardiology, 72(20):2443-2454
Lectura recomendada:
Differential blood pressure effects of ibuprofen, naproxen, and celecoxib in patients with arthritis: the PRECISION-ABPM (Prospective Randomized Evaluation of Celecoxib Integrated Safety Versus Ibupro
European Heart Journal, 38(44):3282-3292
Lectura recomendada:
Direct Oral Anticoagulants for Stroke Prevention in Atrial Fibrillation: Treatment Outcomes and Dosing in Special Populations
Therapeutic Advances in Cardiovascular Disease, 12(9):247-262
Lectura recomendada:
Association of US State Implementation of Newborn Screening Policies for Critical Congenital Heart Disease With Early Infant Cardiac Deaths
JAMA, 318(21):2111-2118
Lectura recomendada:
Extreme high high-density lipoprotein cholesterol is paradoxically associated with high mortality in men and women: two prospective cohort studies
European Heart Journal, 38(22):2478-2486
Lectura recomendada:
Fluoroquinolone use and risk of aortic aneurysm and dissection: nationwide cohort study
BMJ, 360(678):1-8
¿Cuáles son los efectos cardiovasculares de los inhibidores de PCSK9?
Introducción:
Aunque las estatinas representan la primera opción de tratamiento en los sujetos con hipercolesterolemia, algunos enfermos no toleran estos fármacos o no logran las cifras deseadas de colesterol. Los inhibidores de PCSK9 serían útiles en estos casos.
Lectura recomendada:
Effect of PCSK9 Inhibitors on Clinical Outcomes in Patients With Hypercholesterolemia: A Meta?Analysis of 35 Randomized Controlled Trials
Journal of the American Heart Association, 6(12):1-55
Lectura recomendada:
Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
JAMA Network Open, 2(4):1-14