Bioquímica

SERUM LACTATE AS A PROGNOSTIC MARKER IN PEDIATRIC CARDIAC SURGERY PATIENTS
Trend in arterial lactate level during peri-operative period can be a useful tool to assess the prognosis in postoperative period in cardiac surgery in pediatric patients. In the present study, non-survivors had significant persistent elevation in lactates (> 4.0 mmol/l). Similarly, peak lactates in survivors correlated significantly with longer duration of cardiopulmonary bypass, mechanical ventilation and pediatric intensive care unit stay.

Naresh Aggarwal
Bhopal, In

     
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VASCULAR ENDOTHELIAL GROWTH FACTOR IN OVARIAN SEROUS CANCERS
Ovarian serous carcinomas (OSCs) express vascular endothelial growth factor (VEGF) in about 80% of cases, although their effect on tumour proliferation was not confirmed. Though the proliferative activity in OSCs is influenced by many growth factors, VEGF increases the intratumoral micro vessel density, thereby having an indirect effect on tumour proliferation.

Gayatri Ravikumar
Bangalore, In

  
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  TOXICOLOGICAL RISK ASSESSMENT OF SELECTED SMOKELESS TOBACCO PRODUCTS
An attempt has been made to estimate the moisture content, pH (and thus the free nicotine) and to quantify trace metals in a few smokeless tobacco products popular among the locals. These assessments have contributed towards establishing a toxicological fingerprint on the diverse arrays of such products freely available in the market currently.

B Ranganahan
Kochi, IN

  
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EFICIENCIA DE AMPLIFICACIÓN DEL VIRUS DEL DENGUE
La porción distal de la región NS del Virus del Dengue es específica de serotipo y bien conservada permitiendo su eficiente uso para la amplificación de los virus circulantes en Venezuela y posiblemente en las Américas.

María Inés Odreman-macchiolo
Merida, Venezuela

     
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  THE SYSTEM XC- TRANSPORTER AND CANCER-INDUCED BONE PAIN
Cancer cells exist in conditions of elevated oxidative stress. To protect themselves, cancer cells increase the activity of a transport system called system xc- to import necessary cystine in exchange for glutamate. This glutamate is a cell-signalling molecule that has significant implications for bone cell metabolism and pain sensation.

Gurmit Singh
Hamilton, Ca

  
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