Bibliografía del artículo
1. Kalant H. Research on tolerance: What can we learn from history? Alcohol Clin Exp Res 22:67-76, 1998.
2. Chandler JL, Harris RA, Crews TF. Ethanol tolerance and synaptic plasticity. Trends Pharmacol Sci 19:491-95, 1998.
3. Crabbe JC, Rigter H, Vijlen J, Strijbos C. Rapid development of tolerance to the hypothermic effect of ethanol in mice. J Pharmacol Exper Ther 208:128-33, 1979.
4. Barbosa ADE, Morato GS. Influence of neurosteroids on the development of rapid tolerance to ethanol in mice. Eur J Pharmacol 431:179-88, 2001.
5. Barreto PS, Lemos T, Morato GS. NMDA-receptor antagonists block the development of rapid tolerance to ethanol in mice. Addict Biol 3:55-64, 1998.
6. Rustay NR, Crabbe JC. Genetic analysis of rapid tolerance to ethanol's incoordinating effects in mice: inbred strains and artificial selection. Behav Genet 34(4):441-51, 2004.
7. Chan AWK, Schanley DL, Aleo MDE, Leong FW. Cross-tolerance between ethanol and chlordiazepoxide. Alcohol 2:209-13, 1985.
8. Khanna JM, Kalant H, Weiner J, Chau A. Rapid tolerance and cross tolerance as predictors of chronic tolerance and cross-tolerance. Pharmacol Biochem Behav 41:355-60, 1992.
9. Bowen CA, Purdy RH, Grant KA. Ethanol-like discriminative stimulus effects of endogenous neuroactive steroids: effect of ethanol training dose and dosing procedure. J Pharmacol Exp Ther 289:405-11, 1999.
10. Vanover KE, Suruki M, Robledo S, e col. Positive allosteric modulators of the GABAA receptor: differential interaction of benzodiazepines and neuroactive steroids with ethanol. Psychopharmacology 141:77-82, 1999.
11. Mihic SJ. Acute effects of ethanol on GABA-A and glycine receptor function. Neurochemistry International 35:115-23, 1999.
12. Pandey SC. Neuronal signaling systems and ethanol dependence. Mol Neurobiol 17:1-15, 1998.
13. Snell LD, Claffey DJ, Ruth JA, e col. Novel structure having antagonist actions at both the glycine site of the N-methyl-D-aspartate receptor and neuronal voltage-sensitive sodium channels: biochemical, electrophysiological, and behavioral characterization. J Pharmacol Exp Ther 292:215-27, 2000.
14. Venkov CD, Myers PR, Tanner MA, Su M, Vaughan DE. Ethanol increases endothelial nitric oxide production through modulation of nitric oxide synthase expression. Thromb Haemost 81:638-42, 1999.
15. Allan AM, Mayes CG, Draski LJ. Gamma-aminobutyric acid-actived chloride channels in rats selectively bred for differential acute sensitivity to alcohol. Alcohol Clin Exp Res 15(2):212-18, 1991.
16. Vandergriff JL, Mathews DB, Best PJ, Simson PE. Effects of ethanol and diazepam on spatial and non-spatial tasks in rats on an 8-arm maze. Alcohol Clin Exp Res 19:64, 1995.
17. White AM, Simson PE, Best PJ. Comparison between the effects of ethanol and diazepam on spatial working memory in the rat. Psychopharmacology 133:256-61, 1997.
18. Devaud LL, Smith FD, Grayson DR, Morrow AL. Chronic ethanol consumption differentially alters the expression of -aminobutyric acid receptor subunit mRNAs in rat cerebral cortex: competitive, quantitative reverse transcriptase-polymerase chain reaction analysis. Mol Pharmacol 48:861-68, 1995.
19. Devaud LL, Fritschy JM, Sieghart W, Morrow AL. Bi-directional alterations of GABA-A receptors subunit peptide levels in rat cortex during chronic ethanol consumption and withdrawal. J Neurochem 69:126-30, 1997.
20. Baulieu EE. Neurosteroids: of the nervous system, by the nervous system, for the nervous system. Rec Prog Res 52:1-32, 1997.
21. Compagnone NA, Mellon SH. Neurosteroids: Biosynthesis and function of these novel neuromodulators. Frontiers in Neuroendocrinology 21:1-56, 2000.
22. Bowen CA, Purdy RH, Grant HA. An investigation of endogenous neuroactive steroid-induced modulation of ethanol's discriminative stimulus effects. Behav Pharmacol 10(3):297-311, 1999.
23. Lambertt JJ, Belelli D, Hill-Venning C, Peters JA. Neurosteroids and GABA-A receptor function. Trends Pharmacol Sci 16:295-303, 1995.
24. Leœkiewicz M, Budziszewska B, Jaworska-Feil L, Kubera M, Basta-Kaim A, Lasoñ W. Inhibitory effect of some neuroactive steroids on cocaine-induced kindling in mice. Pol J Pharmacol 55:1131-36, 2003.
25. Finn DA, Roberts AJ, Lotrich F, Gallaher EJ. Genetic differences in behavioral sensitivity to a neuroactive steroid. J Pharmacol Exp Ther 280:820-828, 1997.
26. Gasior M, Carter RB, Witkin JM. Neuroactive steroids: potential therapeutic use in neurological and psychiatric disorders. Trends Pharmacol Sci 20:107-112, 1999.
27. De Brito Fature C, Teixeira-Silva F, Leite JR. The anxiolytic effect of pregnancy in rats is reversed by finasteride. Pharmacol Biochem Behavior 85(3):569-74, 2006.
28. Lambert JJ, Belelli D, Peden DR, Vardy AW, Peters JA. Neurosteroid modulation of GABAA receptors. Prog Neurobiol 71:67-80, 2003.
29. Concas A, Mostallino MC, Porcu P, e col. Role of brain allopregnanolone in the plasticity of gamma-aminobutyric acid type A receptor in rat brain during pregnancy and after delivery. Proc Natl Acad Sci USA 95:13284-13289, 1998.
30. Corpechot C, Collins BE, Carey MP, Tsouros A, Robel P, Fry JP. Brain neurosteroids during the mouse estrous cycle. Brain Res 766:276-280, 1997.
31. Genazzani AD, Luisi M, Malavasi B, e col. Pulsatile secretory characteristics of allopregnanolone, a neuroactive steroid, during the menstrual cycle and in amenorrheic subjects. Eur J Endocrinol 146:347-356, 2002.
32. Herbison AE. Physiological roles for the neurosteroid allopregnanolone in the modulation of brain function during pregnancy and parturition. Prog Brain Res 133:39-47, 2001.
33. Palumbo MA, Salvestroni C, Gallo R, e col. Allopregnanolone concentration in hippocampus of prepubertal rats and female rats throughout estrous cycle. J Endocrinol Invest 18:853-856, 1995.
34. Barbosa ADE, Morato GS. Effect of epipregnanolone and pregnenolone sulfate an chronic tolerance to ethanol. Pharmacol Biochem Behav 67:459-64, 2000.
35. Barbosa ADE, Morato GS. Pregnenolone sulfate, dehydroepiandrosterone sulfate and allotetrahydrodeoxycorticosterone affect rapid tolerance to the hypothermic effect of ethanol. Brain Res Bulletin 58:99-05, 2002.
36. Debatin, T, Barbosa, ADE. Effect of isopregnanolone on rapid tolerance to the anxiolytic effect of ethanol. Rev Bras Psiquiatr 28(1):18-23, 2006.
37. Melchior CL, Allen PM. Interaction of pregnanolone and pregnenolone sulfate with ethanol and pentobarbital. Pharmacol Biochem Behav 42:605-11, 1992.
38. Barbaccia ML, Affricano D, Trabucchi M, e col. Ethanol markedly increases GABAergic neurosteroids in alcohol-preferring rats. Eur J Pharmacol 384:R1-R2, 1999.
39. O'Dell LE, Alomary AA, Vallee M, Koob GF, Fitzgerald RL, Purdy RH. Ethanol-induced increases in neuroactive steroids in the rat brain and plasma are absent in adrenalectomized and gonadectomized rats. Eur J Pharmacol 484(2-3):241-47, 2004.
40. Zaleski MJB, Nunes-Filho JR, Lemos T, Morato GS. GABAB receptors play a role in the development of tolerance to ethanol in mice. Psychopharmacology 153:415-24, 2001.
41. Crews FT, Morrow AL, Criswell H, Breese G. Effects of ethanol on ion channels. Int Rev Neurobiol 39:283-367, 1996.
42. Grobin AC, Matthews DB, Devaud LL, Morrow AL. The role of GABAA receptors in the acute and chronic effects of ethanol. Psychopharmacology 139:2-19, 1998.
43. Mihic SJ, Ye Q, Wick MJ, e col. Sites of alcohol and volatile anaesthetic action on GABAA and glycine receptors. Nature 389:385-389, 1997.
44. Morrow AL, VanDoren MJ, Penland SN, Matthews DB. The role of GABAergic neuroactive steroids in ethanol action, tolerance and dependence. Brain Res Brain Res Rev 37:98-109, 2001.
45. Martin-García E, Darbra S, Pallarès M. Intrahippocampal allopregnanolone decreases voluntary chronic alcohol consumption in non-selected rats. Proq Neuropsycopharmacology Biol Psychiatry 31(4):823-31, 2007.
46. Kumar S, Fleming RL, Morrow AL. Ethanol regulation of gamma-aminobutyric acid A receptors: genomic and nongenomic mechanisms. Pharmacol Ther 101(3):211-26, 2004.
47. Devaud LL, Alele P. Differential effects of chronic ethanol administration and withdrawal on gamma-aminobutyric acid type A and NMDA receptor subunit proteins in male and female rat brain. Alcohol Clin Exp Res 28(6):957-65, 2004.
48. Yu R, Follesa P, Ticku MK. Down-regulation of the GABA receptor subunits mRNA levels in mammalian cultured cortical neurons following chronic neurosteroid treatment. Brain Res Mol Brain Res 41:163-68, 1996.
49. Devaud LL, Morrow AL, Nguyen UTQ. Ovariectomy has minimal effects on neuroadaptations associated with ethanol dependence in female rats. Neurochem Int 37:433-42, 2000.
50. Reddy S, Kulkarni ML. Differential anxiolytic effects of neurosteroids in the mirrored chamber behavior test in mice. Brai Res 752(1-2):61-71, 1997.
51. Brot MD, Akwa Y, Purdy RH, Koob GF, Briton KT. The anxiolytic-like effects of the neurosteroid allopregnanolone: interactions with GABA(A) receptors. Eur J Pharmacol 325(1):1-7, 1997.
52. Fernández-Guasti A, Picazo O. Flumazenil blocks the anxiolytic action of allopregnanolone. Eur J Pharmacol 281(1):113-115, 1995.