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LA LACTANCIA PROLONGADA SE RELACIONA CON MENORES NIVELES DE LEPTINA EN PACIENTES CON DIABETES MELLITUS GESTACIONAL
(especial para SIIC © Derechos reservados)
La duraci贸n prolongada de la lactancia se asoci贸 con menores niveles de leptina y con mejor perfil metab贸lico en el per铆odo posparto temprano en mujeres con diabetes mellitus gestacional y con embarazo normal, respectivamente.
Autor:
Renata Saucedo
Columnista Experta de SIIC

Institución:
Instituto Mexicano del Seguro Social


Artículos publicados por Renata Saucedo
Artículo comentado
Pablo Ariel Ferrada
M茅dico, especialista en Endocrinolog铆a.
M茅dico de planta, Servicio de Enfermedades Endocrino-Metab贸licas.
Hospital Central de Mendoza, Facultad de Ciencias M茅dicas, Universidad Nacional de Cuyo, Mendoza, Argentina
Coautores
Rosa Galv谩n* Lourdes Basurto** Julio S谩nchez*** Marcelino Hern谩ndez**** Edgardo Puello**** Arturo Z谩rate**** 
Maestra en Ciencias, Instituto Mexicano del Seguro Social, M茅xico DF, M茅xico*
M茅dica, Instituto Mexicano del Seguro Social, M茅xico DF, M茅xico**
Qu铆mico Farmac茅utico, Bi贸logo, Instituto Mexicano del Seguro Social, M茅xico DF, M茅xico***
M茅dico, Instituto Mexicano del Seguro Social, M茅xico DF, M茅xico****
Recepción del artículo
15 de Abril, 2014
Aprobación
2 de Junio, 2014
Primera edición
23 de Junio, 2014
Segunda edición, ampliada y corregida
26 de Junio, 2017

Resumen
Introducci贸n: Las mujeres con diabetes mellitus gestacional (DBTG) tienen un riesgo elevado de presentar diabetes tipo 2 en el posparto. La lactancia materna se ha asociado a una disminuci贸n del riesgo de diversas enfermedades metab贸licas. El objetivo de este estudio fue evaluar el impacto de la duraci贸n de la lactancia sobre niveles de leptina en mujeres con DBTG previa, en comparaci贸n con mujeres con embarazo normal. Materiales y m茅todos: Se realiz贸 un an谩lisis secundario a una base de datos de un estudio prospectivo comparativo en el que se evaluaron en el embarazo y el posparto 43 mujeres con DBTG y 43 embarazadas normotensas eugluc茅micas. Se clasific贸 a las participantes de acuerdo con el tiempo de lactancia materna en duraci贸n breve (menos de 6 semanas) o duraci贸n prolongada (m谩s de 6 semanas a menos de 6 meses) y se determinaron sus niveles de leptina. Resultados: Las mujeres con DBTG que tuvieron una lactancia de duraci贸n prolongada presentaron una mayor disminuci贸n de peso en el posparto y un menor nivel de leptina, en comparaci贸n con las de lactancia materna de duraci贸n breve. Esta diferencia permaneci贸 estad铆sticamente significativa despu茅s del ajuste por el peso de las participantes. En el grupo de control, las mujeres con lactancia de duraci贸n prolongada presentaron menores niveles de triglic茅ridos, insulina y resistencia a la insulina. Conclusiones: La duraci贸n prolongada de la lactancia se asoci贸 con menores niveles de leptina y con mejor perfil metab贸lico en el per铆odo posparto temprano de las mujeres con DBTG previa y con embarazo normal, respectivamente.

Palabras clave
leptina, lactancia materna, diabetes mellitus gestacional, insulina, resistencia a la insulina


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Abstract
Introduction: Women with gestational diabetes mellitus (GDM) have an increased risk of developing type 2 diabetes postpartum. Breastfeeding has been associated with a decreased risk of various metabolic diseases. The aim of this study was to evaluate the impact of the duration of lactation on leptin levels in women with previous GDM compared with women with normal pregnancy. Materials and Methods: We performed a secondary analysis of a database of a prospective comparative study in which we evaluated 43 women with GDM and 43 normotensive ang euglycemic pregnant women at pregnancy and at postpartum. Participants were classified according to the lactation duration in short (< 6 weeks) or long duration (> 6 weeks - < 6 months) and the leptin levels were measured. Results: Compared with women with GDM who lactated < 6 weeks, women with longer duration of lactation showed greater weight loss at postpartum and lower leptin levels. This difference remained statistically significant after adjustment for weight. In control group, women with longer duration of lactation had lower triglyceride and insulin levels, and insulin resistance than women with short duration. Conclusions: The longer duration of breastfeeding was associated with lower levels of leptin and better metabolic profile in the early postpartum period in women with previous GDM and normal pregnancy respectively.

Key words
leptin, breastfeeding, gestational diabetes mellitus, insulin, insulin resistance


Clasificación en siicsalud
Artículos originales > Expertos de Iberoamérica >
página   www.siicsalud.com/des/expertocompleto.php/

Especialidades
Principal: Endocrinolog铆a y MetabolismoObstetricia y Ginecolog铆a
  Relacionadas: Diabetolog铆aNutrici贸nDiagn贸stico por LaboratorioMedicina Familiar

Enviar correspondencia a:
Renata Saucedo, 06720, Avenida Cuauhtemoc 330, M茅xico DF, M茅xico
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Título español
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 Bibliografía
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Artículos originales>
Expertos de Iberoamérica

Especialidad principal:
Endocrinolog铆a y MetabolismoObstetricia y Ginecolog铆a

Relacionadas:
 Diabetolog铆a
 Nutrici贸n
 Diagn贸stico por Laboratorio
 Medicina Familiar
 
 
 
 
 
 
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