Crónicas de autores

María Belén Prados *

Autora invitada por SIIC


MECANISMOS REGULATORIOS DE LA N-GLICOSILACIÓN DE LA IGG MEDIADOS POR PROGESTERONA

La progesterona regula la relación STT3-A/STT3-B, incrementando la N-glicosilación de la IgG1 secretada por el hibridoma 112D5. Este trabajo constituye la primera evidencia de que las isoformas de STT3 pueden ser moduladas hormonalmente y apoya la idea que la completa N-glicosilación de las proteínas requiere la cooperación entre ambas isoformas de la subunidad catalítica de OST.

*María Belén Prados
describe para SIIC los aspectos relevantes de su trabajo
PROGESTERONE INDUCES A SWITCH IN OLIGOSACCHARYLTRANSFERASE ISOFORM EXPRESSION: CONSEQUENCES ON IGG N-GLYCOSYLATION
Immunology Letters,
137(1-2):28-37 Jun, 2011

Esta revista, clasificada por SIIC Data Bases, integra el acervo bibliográfico
de la Biblioteca Biomédica (BB) SIIC.

Institución principal de la investigación
*Instituto de Investigaciones Cardiológicas "Prof. Dr. Alberto C. Taquini" (ININCA), CONICET-Universidad de Buenos Aires, Buenos Aires, Argentina
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