Risk factors for cardiac and renal disease in hypertensive patients with overweight or obesity

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Federico Guerra
describes for SIIC the most significant aspects of his article
describe para SIIC los aspectos relevantes de su artículo

Role of the Metabolic Syndrome
Risk factors for cardiac and renal disease in hypertensive patients with overweight or obesity

Along with BP and BMI, albuminuria measured in a morning urine sample asACRis a valuable low-cost index of cardiac organ damage and increased cardiovascular risk in hypertensive patients independently by MetS. On the other hand, MetS is not an independent risk factor for cardiac damage because it does not seem to add anything more than the sum of each of its components (especially SBP and adiposity indexed by BMI) to the relationship between cardiac and renal subclinical organ damage.

The article was published by
El artículo fue publicado por

High Blood Pressure & Cardiovascular Prevention
Volume / Volumen: 18
Number / Número: 4
First and last pages / Páginas inicial-final: 195-201
Year / Año: 2011
Month / Mes:

This journal, which is covered by SIIC Data Bases,
is part of the bibliographic collections of the Biblioteca Biomédica (BB) SIIC.
Esta revista, clasificada por SIIC Data Bases,
integra el acervo bibliográfico de la Biblioteca Biomédica (BB) SIIC.

Principal institution where the research took place
Institución principal de la investigación
University Hospital ‘‘Ospedali Riuniti’’, Marche Polytechnic University, Ancona, Italy, Ancona, AN, Italy

Authors' Report
Crónica del Autor
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Papel del Síndrome Metabólico
Factores de Riesgo de Daño Cardíaco y Renal en Pacientes con Hipertensión y Sobrepeso u Obesidad

Además de la presión arterial y el índice de masa corporal, la albuminuria -determinada en una muestra de orina matutina como cociente entre albúmina y creatinina- representa un índice de bajo costo para detectar daño cardíaco y riesgo cardiovascular aumentado en los pacientes hipertensos, de manera independiente de la presencia de síndrome metabólico. Por otra parte, el síndrome metabólico no constituye per se un factor de riesgo de daño cardíaco, ya que no aporta más información que la sumatoria de cada uno de sus componentes (especialmente la presión arterial sistólica y la adiposidad, determinada por el índice de masa corporal) a la relación entre el daño subclínico cardíaco y renal.

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Bibliographic references
Referencias bibliográficas

1. Mancia G, Laurent S, Agabiti-Rosei E, et al. Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. J Hypertens 27:2121-2158, 2009.
2. De Zeeuw D. Albuminuria: a target for treatment of type 2 diabetic nephropathy. Semin Nephrol 27:172-181, 2007.
3. Mancia G, De Backer G, Dominiczak A, et al. Management of Arterial Hypertension of the European Society of Hypertension; European Society of Cardiology. 2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 25:1105-1187, 2007.
4. Schmieder RE. The role of non-hemodynamic factors of the genesis of LVH. Nephrol Dial Transplant 20:2610-2612, 2005.
5. Ruilope LM, Schmieder RE. Left ventricular hypertrophy and clinical outcomes in hypertensive patients. Am J Hypertens 21:500-508, 2008.
6. Cuspidi C, Meani S, Fusi V, et al. Metabolic syndrome and target organ damage in untreated essential hypertensives. J Hypertens 22:1991-1998, 2004.
7. Guerra F, Mancinelli L, Angelini L, et al. The association of left ventricular hypertrophy with metabolic syndrome is dependent on body mass index in hypertensive overweight or obese patients. PLoS ONE 6:e16630, 2011.
8. Reaven G. The metabolic syndrome: requiescat in pace. Clin Chem 51:931-938, 2005.

Other articles written by the author Federico Guerra
Otros artículos de Federico Guerra

Sarzani R, Salvi F, Bordicchia M, Guerra F,. Battistoni I, Pagliariccio G, Carbonari L, Dessı`-Fulgheri P, Rappelli A. Carotid artery atherosclerosis in hypertensive patients with a functional LDL receptor-related protein 6 gene variant. Nutrition, Metabolism and Cardiovascular Disease 2011; 21: 150-156.

Guerra F, Mancinelli L, Angelini L, Fortunati M, Rappelli A, Dessì-Fulgheri P, Sarzani R. The association of left ventricular hypertrophy with metabolic syndrome is dependent on body mass index in hypertensive overweight or obese patients. PLoS ONE 2011 (6); e16630.

Capucci A, Guerra F. Late postoperative atrial fibrillation: minor surgery complication or major cardiovascular issue? Journal of Cardiovascular Medicine 2011; 12: 381–382.

Guerra F, Mancinelli L, Buglioni A, Pierini V, Rappelli A, Dessì-Fulgheri P, Sarzani R. Microalbuminuria and left ventricular mass in overweight and obese hypertensive patients: role of the metabolic syndrome. High Blood Pressure and Cardiovascular Prevention 2011; 18: 195-201.

Capucci A, Guerra F, Antenucci C, Antonicelli R, Bocconcelli P, Boriani G, Busacca P, Ciampani N, Della Casa S, Gabrielli D, Galvani M, Margheri M, Melandri F, Modena MG, Perna GP, Pieri P, Piovaccari G, Pozzolini A, Rapezzi C, Villani GQ. Dronedarone: una reale innovazione o solo una valida seconda scelta? Come districarsi tra linee guida, agenzie regolatorie e pratica clinica quotidiana. Giornale Italiano di Cardiologia 2012; 18: 326-333.

Sarzani R, Guerra F, Mancinelli L, Buglioni A, Franchi E, Dessì-Fulgheri P. Plasma aldosterone is increased in class 2 and 3 obese hypertensive patients despite drug treatment. American Journal of Hypertension 2012; in press.

Sarzani R, Guerra F. Obesity and hypertension in cardiac hypertrophy: two sides of the same coin? High Blood Pressure and Cardiovascular Prevention 2012; in press.

Fedecostante M, Barbatelli P, Guerra F, Espinosa E, Dessì-Fulgheri P, Sarzani R. Summer does not always mean lower: seasonality of 24 hours, daytime and night-time blood pressure. Journal of Hypertension 2012; in press.

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The authors' report was accepted on La crónica del autor fue aprobada el 2023, october 21	Published in siicsalud Publicado en siicsalud 2024, january 19

The article is strictly related to the following sections of siicsalud
El artículo se relaciona estrictamente con las siguientes secciones de siicsalud

Cardiology
/ Cardiología

Nephrology
/ Nefrología y Medio Interno

and secondarily related to the following sections
y secundariamente con las siguientes secciones

Primary Care
Atención Primaria

Biochemistry
Bioquímica

Clinical Cardiology
Cardiología Clínica

Hypertension
Hipertensión Arterial

Clinical Chemistry
Diagnóstico por Laboratorio

Endocrinology and Metabolism
Endocrinología y Metabolismo

Family Medicine
Medicina Familiar

Internal Medicine
Medicina Interna

Clinical Nephrology
Nefrología Clínica

Information about the full text
Acerca del trabajo completo

Microalbuminuria and Left Ventricular Mass in Overweight and Obese Hypertensive Patients: Role of the Metabolic Syndrome

Author / Autor
Federico Guerra¹, Lucia Mancinelli², Alessia Buglioni³, Valentina Pierini⁴, Alessandro Rappelli⁵, Paolo Dessì-Fulgheri⁶, Riccardo Sarzani⁷

7 Prof.

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High Blood Pressure & Cardiovascular Prevention

Article URL: / URL del artículo:
http://adisonline.com/highbloodpressure/Pages/default.aspx
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