Conceptos Categóricos

PLEURESÍA TUBERCULOSA COMO MANIFESTACIÓN DE RECONSTITUCIÓN INMUNE EN UN PACIENTE CON SIDA

El síndrome inflamatorio de reconstitución inmune (SIRI) es una complicación importante y temprana en respuesta a la implementación de la terapia antirretroviral de gran actividad. Se describe un paciente con sida que presentó pleuresía por M. tuberculosis como manifestación de SIRI, luego de 2 meses del inicio de la terapia antirretroviral.
Autor
Analía Boschi
Columnista Experta de SIIC
Institución del autor
Hospital de Infecciosas F. J. Muñiz, Buenos Aires, Argentina
Coautores
Marcelo Corti*   
Hospital de Infecciosas F. J. Muñiz, Buenos Aires, Argentina*

Clasificación en siicsalud
Artículos originales > Expertos del Mundo >
página  http://siicsalud.com/dato/casiic.php/133653

Especialidades
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Primera edición
19 de marzo, 2013
Segunda edición, ampliada y corregida
14 de abril, 2014

Bibliografía del caso clínico
1. Lawn SD, Bekker LG, Miller RF. Immune reconstitution disease associated with mycobacterial infections in HIV-infected individuals receiving antiretrovirals Lancet Infectious Diseases 5:361-73, 2005.
2. Cheng VC, Ho PL, Lee RA, et al. Clinical spectrum of paradoxical deterioration during anti-tuberculosis therapy in non-HIV-infected patients, Eur J Clin Microbiol Infect Dis 21:803-9, 2002.
3. Orlovic D, Smego RA Jr. Paradoxical tuberculous reactions in HIV-infected patients. Int J Tuber Lung Dis 5:370-5, 2001.
4. Gopi A, Madhavan SM, Sharma SK, Sahn SA. Diagnosis and treatment of tuberculous pleural effusion in 2006. Chest 131:880-9, 2007.
5. Al-Majed SA. Study of paradoxical response to chemotherapy in tuberculous pleural effusion. Respir Med 90:211-4, 1996.
6. Sterne JA, Hernán MA, Ledergerber B, et al. The Swiss Cohort Study. Long-term effectiveness of potent antiretroviral therapy in preventing AIDS and death: a prospective cohort study. Lancet 366:378-84, 2005.
7. Battegay M, Nüesch R, Hirschel B, Kaufmann GR. Immunological recovery and antiretroviral therapy in HIV infection. Lancet Infect Dis 6:280-7, 2006.
8. Müller M, Wandel S, Colebunders R, et al. Immune reconstitution inflammatory syndrome in patients starting antiretroviral therapy for HIV infection: a systematic review and meta-analysis. Lancet Infect Dis 10:251-61, 2010.
9. Kumarasamy N, Chaguturu S, Mayer KH, et al. Incidence of immune reconstitution syndrome in HIV/tuberculosis-coinfected patients after initiation of generic antiretroviral therapy in India. J Acquir Immune Defic Syndr 37:1574-6, 2004.
10. Narita M, Ashkin D, Hollender ES, Pitchenik AE. Paradoxical worsening of tuberculosis following antiretroviral therapy in patients with AIDS. Am J Respir Crit Care Med 158:157-61, 1998.
11. Shelbourne SA, Visnegarwala F, Darcourt J, et al. Incidence and risk factors for immune reconstitution inflammatory syndrome during highly active antiretroviral therapy. AIDS 19:399-406, 2005.
12. Ratnam I, Chiu C, Kandala NB, Easterbrook PJ. Incidence and risk factors for immune reconstitution inflammatory syndrome in an ethnically diverse HIV type 1-infected cohort. Clin Infect Dis 42:418-27, 2006.
13. Phillips P, Bonner S, Gataric N, et al. Nontuberculous mycobacterial immune reconstitution syndrome in HIV-infected patients: spectrum of disease and long-term follow-up. Clin Infect Dis 41:1483-97, 2005.
14. Jeon K, Choi WI, An JS, et al. Paradoxical response in HIV-negative patients with pleural tuberculosis: a retrospective multicentre study. Int J Tuberc Lung Dis 16:846-51, 2012.
15. Adeiza MA. Tuberculosis-associated immune reconstitution inflammatory syndrome: Management challenges in resource-limited settings. Ann Nigerian Med 6:1-3, 2012.
16. Corti M, Palmero D, Trione N, Semorile K, Yampolsky C, Ambroggi M, Schtirbu R. Cerebral abscess associated with multidrug-resistant tuberculosis and immune reconstitution. Int J Tuberc Lung Dis 10:14-17, 2006.
Artículos publicados por el autor (selección)
Human Mycobacterium bovis infection in Buenos Aires: epidemiology, microbiology and clinical presentation International Journal of Tuberculosis and Lung Disease 16:415-417, 2012

Reactivation of Chagas disease with central nervous system involvement in HIV-infected patients in Argentina, 1992-2007 International Journal of Infectious Diseases 12:587-592, 2008



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